From Literary Metaphors in Wonderland and the Looking-Glass World to Clinical Condition: The Alice Syndrome

Authors:

Pages: 99-110
DOI: https://doi.org/10.54664/CYUK7286

Abstract:

Alice in Wonderland Syndrome (AIWS) represents a complex multisensory phenomenon, characterized by transient disturbances in the perception of the body and visual experience. Clinical manifestations include micropsia, macropsia, teleopsia, distorted time perception, and derealization. Contemporary neuroimaging and neurophysiological evidence indicate that dysfunctions in cortical networks, as well as in the temporo-parietal-occipital junction, disrupt the coordination between the embodied self and visual perception. Furthermore, neurotransmitter systems including serotonergic, glutamatergic, and GABAergic pathways may modulate cortical excitation and inhibition. These findings underscore the necessity for multidisciplinary research to elucidate the pathophysiological mechanisms underlying AIWS and to guide the development of targeted therapeutic strategies.

Keywords:

Alice in Wonderland Syndrome, perception of the body, visual experience, micropsia, macropsia, teleopsia, distorted time perception, derealization

Download

NA